Cancer and vegetables and fruit research

We have listed below the key review papers and studies that have addressed the issue of cancer and consumption of vegetables and fruit. (Please note: Research examining wholefood plant based diet and vegetarian diets is listed separately).                            Last updated:   June 22nd 2010 

General research on fruit and vegetable consumption

Research review papers:

Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk. Riboli E & Norat T. Am J Clin Nutr.  2003 Sep;78(3 Suppl):559S-569S. (Full text)

Dietary intervention strategies to modulate prostate cancer risk and prognosis. Freedland SJ & Aronson WJ. Curr Opin Urol 2009 May;19(3):263-7 (Abstract)

Dietary polyphenols, inflammation, and cancer. Guo W et al. Nutr Cancer. 2009 Nov;61(6):807-10. (Abstract)

Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials. Block KI et al. Int J Cancer. 2008 Sep 15;123(6):1227-39. (Abstract)

Prostate cancer and vegetable consumption. Chan R et al. Mol Nutr Food Res. 2009 Feb;53(2):201-16. (Abstract)

Bioactive food components and cancer risk reduction. Stan SD et al. J Cell Biochem 2008 May 1;104(1):339-56. (Abstract)

Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials. Naithani R et al. Curr Med Chem. 2008;15(11):1044-71. (Abstract)

Association between fruit and vegetable consumption and oral cancer: a meta-analysis of observational studies. Pavia M et al. Am J Clin Nutr. 2006 May;83(5):1126-34. (Full text)

Key research studies:

Consumption of vegetables and fruit and the risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition. Buchner FL. Int J Cancer. 2009 Dec 1;125(11):2643-51. (Abstract)

Fruits, vegetables and the risk of cancer: a multisite case-control study in Uruguay. Aune D et al. Asian Pac J Cancer Prev. 2009 Jul-Sep;10(3):419-28. (Abstract)

Fruit and vegetable intake and overall cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). Boffetta P et al. J Natl Cancer Inst. 2010 Apr 21;102(8):529-37. (Abstract)

Oxidative stress-related genotypes, fruit and vegetable consumption and breast cancer risk. Li Y et al. Carcinogenesis. 2009 May;30(5):777-84. (Full text)

Cruciferous vegetables (Broccoli, Cabbage, Cauliflower, Brussels sprouts, Kale, Bok choy)

Research review papers

Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk. Lee SA et al. Am J Clin Nutr. 2008 Mar;87(3):753-60. (Full text)

Cruciferous vegetable consumption and lung cancer risk: a systematic review. Lam TK et al. Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):184-95. (Full text)

Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Higdon JV et al. Pharmacol Res. 2007 Mar;55(3):224-36. (Full text)

Organosulfur compounds in cancer chemoprevention. Moriarty RM et al. Mini Rev Med Chem.  2007 Aug;7(8):827-38. (Abstract)

Organoselenium compounds in cancer chemoprevention. Naithani R, Mini Rev Med Chem. 2008 Jun;8(7):657-68. (Abstract)

Intake of Cruciferous Vegetables Modifies Bladder Cancer Survival. Tang L et al Cancer Epidemiol Biomarkers Prev. 2010 Jun 15. (Abstract)

Garlic, onions (Allium vegetables)

Organosulfur compounds in cancer chemoprevention. Moriarty RM et al. Mini Rev Med Chem.  2007 Aug;7(8):827-38. (Abstract)

Organoselenium compounds in cancer chemoprevention. Naithani R, Mini Rev Med Chem. 2008 Jun;8(7):657-68. (Abstract)

Tomatoes

Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Haseen F et al. Prostate Cancer Prostatic Dis. 2009;12(4):325-32. (Abstract)

Diet and dietary supplement intervention trials for the prevention of prostate cancer recurrence: a review of the randomized controlled trial evidence. Van Patten CL et al. J Urol. 2008 Dec;180(6):2314-21. (Abstract)

Lycopene in the prevention of prostate cancer. Dahan K et al. J Soc Integr Oncol. 2008 Winter;6(1):29-36. (Abstract)

Tomatoes versus lycopene in oxidative stress and carcinogenesis: conclusions from clinical trials. Basu A & Imrhan V. Eur J Clin Nutr. 2007 Mar;61(3):295-303. (Abstract)

Citrus fruits

Citrus fruit intake and pancreatic cancer risk: a quantitative systematic review. Bae JM et al. Pancreas. 2009 Mar;38(2):168-74. (Abstract)

Citrus fruits intake and prostate cancer risk: a quantitative systematic review. Bae JM et al. J Prev Med Public Health. 2008 May;41(3):159-64. (Full text)

Citrus fruit intake and stomach cancer risk: a quantitative systematic review. Bae JM et al. Gastric Cancer. 2008;11(1):23-32. Epub 2008 Mar 29.

Apples

Cancer chemopreventive potential of apples, apple juice, and apple components. Gerhauser C. Planta Med. 2008 Oct;74(13):1608-24. (Abstract)

Berries

Cranberry and blueberry: evidence for protective effects against cancer and vascular diseases. Neto CC. Mol Nutr Food Res. 2007 Jun;51(6):652-64. (Abstract)

Laboratory and clinical studies of cancer chemoprevention by antioxidants in berries. Stoner GD et al. Carcinogenesis. 2008 Sep;29(9):1665-74. (Full text)

Other fruits

Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products. Kaur M et al. J Nutr. 2009 Sep;139(9):1806S-12S. (Abstract)

Cancer chemoprevention by pomegranate: laboratory and clinical evidence. Adhami Vm et al. Nutr Cancer. 2009 Nov;61(6):811-5. (Abstract)

 

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